Hormone
Replacement Therapy (HRT)
Estrogen levels drop dramatically at menopause, and
HRT attempts to replace this hormone for maximum bone
protection. Progestin is sometimes added to estrogen
to decrease the risk of uterine cancer. There is no
question that HRT dramatically reduces fracture risk
and builds bone, there are risks of breast cancer,
heart disease, and blood clots with prolonged use,
as well as potential risk of menopausal side effects.
Biophosphanates
Alendronate, brand name Fosamax , Risedronate, brand
name Actonel
Biophosphanates are compounds that slow the loss of
bone, and improve bone strength. Fosamax is approved
for the prevention and treatment of post-menopausal
and glucocortocoid-induced osteoporosis, for women
and men. It decreases bone fractures of the spine,
wrist, and hip. It's chief risk factors are stomach
upset and burning of the esophagus.
NEW! BONIVA Ibandronate Sodium Tablets
The first ONCE-A-MONTH biophosphanate tablet for
the treatment of
post-menopausal Osteoporosis! Only one pill a month!
Selective
Estrogen Receptor Modulators
Raloxifene, brand name Evista
SERMS are drugs that work like estrogen on bone, but
with fewer side effects. Evista is approved for the
treatment and prevention of post-menopausal Osteoporosis.
It prevents bone loss in the spine, less so in the
hip and total body, and produces small increases in
bone mass. Its major risk factors are blood clots
and hot flashes.
Miacalcin
Brand name Calcitonin
Calcitonin is a naturally-occuring hormone involved
in calcium regulation, approved for the treatment
- not prevention - of Osteoporosis. It controls bone
breakdown, relieves bone fracture pain, and reduces
bone loss, especially in the spine. It's available
via injection, and more commonly as a nasal spray.
Side effects are an itchy or runny nose.
Teriparatide
Brand Name Forteo
Just approved: the first medication to build bone!
Forteo stems from the parathyroid hormone, and greatly
reduces fracture risk at the spine and hip. It's available
via injection to post-menopausal women and men at
high risk of fracture. Not recommended for patients
at risk for bone cancer or Paget's disease.
Click
here to take the 'Osteoporosis risk-factor' test